• 27 Feb 2017

    ALLOIMMUNE THROMBOCYTOPENIA

    Neonatal alloimmune thrombocytopenia occurs when the mother is homozygous for an uncommon platelet alloantigen, most often PlA2 on gplIla, and the fetus expresses the PlAi haplotype inherited ...

  • 27 Feb 2017

    Evaluation of Leukopenia

    Neutropenia can reflect decreased production, increased sequestration, or peripheral destruction of neutrophils. Patients should first be evaluated for splenomegaly rule out the possibility of ...

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  • Neonatal alloimmune thrombocytopenia occurs when the mother is homozygous for an uncommon platelet alloantigen, most often PlA2 on gplIla, and the fetus expresses the PlAi haplotype inherited from the father. The pathogenesis of alloimmune thrombocytopenia is analogous to the mechanism by which Rh sensitization induces hemolytic disease of the newborn. The mother is exposed to...

  • Neutropenia can reflect decreased production, increased sequestration, or peripheral destruction of neutrophils. Patients should first be evaluated for splenomegaly rule out the possibility of sequestration In patients who are completely asymptomatic and in whom previous studies are unavailable, the possibility of congenital or cyclic neutropenia should be entertained and can be evaluated by serial peripheral...

  • Clinicians have multiple tests at their disposal when evaluating a patient with chronic diarrhea, and proper judgment should be used in choosing the most appropriate ones. Duration of diarrhea, evidence of systemic involvement, nutritional deficiencies and previous investigations should guide the evaluation of the patient. In contrast to acute diarrhea, infectious etiology is uncommon with...

  • H. pylori is a gram-negative curved, flagellated rod found only in gastric epithelium or in gastric metaplastic epithelium. H. pylori clearly causes histologic gastritis and is found in 80% to patients with duodenal ulcers and 70% to 90% of patients with gastric ulcers. However, only a minority of patients with H. pylori gastritis develop peptic...

  • Classic symptoms of acute pancreatitis include acute abdominal pain, nausea, and vomiting. Physical examination may reveal reduced bowel sounds secondary to ileus, jaundice resulting from gallstones abdominal tenderness, fever, or tachycardia. Acute in to the results in leakage of pancreatic enzymes into the blood stream. This condition is detected as an increase in serum amylase...